产品货号：
Z20479
中文名称：
MEK6/MAP2K6抗体
英文名称：
Anti-MEK6/MAP2K6 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-MEK6/MAP2K6 Antibody |
| 指标别名 | MAP kinase kinase 6;MAP2K6;MAPK/ERK kinase 6;MAPKK 6;MAPKK6;MEK 6;MEK6;MKK6;PRKMK6;SAPKK3 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB |
| 基因名称 | MAP2K6 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the N-terminus of human MEK6(7-23aa KKRNPGLKIPKEAFEQP),identical to the related mouse sequence and different from the related rat sequence by one amino acid. |
| 实际分子量 | 38KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | MAP2K6(Mitogen-activated protein kinase kinase 6),also known as MAP kinase kinase 6(MAPKK 6) or MAPK/ERK kinase 6 is an enzyme that in humans is encoded by the MAP2K6 gene,on chromosome 17.MAPKK 6 is a member of the dual specificity protein kinase family,which functions as a mitogen-activated protein(MAP) kinase kinase.Han et al.(1996) described experiments addressing the function of MKK6 in intracellular signaling pathways leading toward activation of p38 MAPK.Mukherjee et al.(2006) found that the Yersinia YopJ virulence factor acted as an acetyltransferase,using coenzyme A to modify critical ser and thr residues in the MAP2K6 activation loop,thereby blocking phosphorylation and kinase activation.They proposed that ser and/or thr acetylation by a bacterial effector may be a mechanism that occurs in other signaling pathways. |
| Uniprot ID | P52564 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | mitogen-activated protein kinase kinase 6 |
| 蛋白名全称 | Dual specificity mitogen-activated protein kinase kinase 6 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 |
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